natsel_sitehet – a test of site heterogeneity

This app evaluates evidence for whether sites differ in their mode of natural selection (Nielsen and Yang 1998).

The models have been constructed such that site-class bins have names indicating the mode of natural selection: -ve is purifying (oomega<1); neutral (omega=1); and +ve is positive natural selection (omega>1). The two parameters of interest relating to these are the bprobs (the maximum likelihood estimate of the frequency of the site-class) and the corresponding value of omega.

Getting the individual site posterior probabilities

I’m just displaying the posterior-probabilities from the first 20 positions only.